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SRX17893303: GSM6641836: P23-45_t5_enriched; Thermus thermophilus HB8; RNA-Seq
1 OXFORD_NANOPORE (PromethION) run: 3.1M spots, 904M bases, 757.3Mb downloads

External Id: GSM6641836_r1
Submitted by: Laboratory of Gene Technology, Biosystems, KU Leuven
Study: ONT-cappable-seq for P23-45 bacteriophage 5 min post-infection
show Abstracthide Abstract
We performed the long-read RNA sequencing technique ONT-cappable-seq on RNA samples of T. thermophilus infected with phage P23-45 5 minutes post-infection. Using this approach, we obtained the primary transcriptome at the early infection stage and sequenced it in full-length. Based on this data, we were able to identify viral transcription start sites and termination sites and uncover distinct promoter motifs. Overall design: Full-length transcriptional profiling of T. thermophilus infected with phage P23-45 at 5min post-infection using ONT-cappable-seq.
Sample: P23-45_t5_enriched
SAMN31285980 • SRS15410802 • All experiments • All runs
Library:
Name: GSM6641836
Instrument: PromethION
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: SINGLE
Construction protocol: Total RNA was extracted using the TRIzol method, followed by Dnase I treatment. The enriched sames were subjected to an enrichment procedure based on streptavidin beads to enrich for primary RNA transcripts. For the control samples the enrichment steps were omitted. Total RNA was enriched for primary transcripts using the ONT-cappable-seq enrichment protocol. In paralel, the control samples were subjected to similar environmental conditions. The RNA was reverse transcribed, PCR amplified and barcoded according to the Oxford Nanopore Technologies cDNA-PCR protocol (SQK-PCS109 combined with SQK-PBK004). The amplified cDNA samples were pooled together in a final library.
Runs: 1 run, 3.1M spots, 904M bases, 757.3Mb
Run# of Spots# of BasesSizePublished
SRR219072743,068,408904M757.3Mb2023-12-12

ID:
24826977

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